What is the most significant complication associated with CVAD placement?

• A. Thrombosis
• B. Infection, specifically CLABSIs
• C. Air embolism
• D. Catheter misplacement

Answer: (B)

The most significant complication associated with central vascular access device (CVAD) placement is infection, specifically central line-associated bloodstream infections (CLABSIs). CLABSIs are serious infections that can occur when bacteria or other pathogens enter the bloodstream through the catheter. The risk of CLABSIs is a major concern in healthcare settings, particularly for patients with CVADs, as they frequently require prolonged access to the vascular system.

Infections can lead to severe complications, including sepsis, prolonged hospital stays, increased healthcare costs, and even death in critically ill patients. Therefore, maintaining strict aseptic techniques during insertion and care of the CVAD is essential in minimizing this risk. This emphasizes the importance of education and adherence to protocols for both healthcare personnel and patients.

While other complications such as thrombosis, air embolism, and catheter misplacement can also occur and pose risks, CLABSIs have a more significant impact on patient safety and outcomes given their potential severity and the challenges they present in management and prevention.